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Who was studied 188,039 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.031 z score lower (95% confidence interval 0.021-0.041); p = 1 × 10−9.
How common The A allele had a frequency of about 11% in the people studied.
Where it sits Chromosome 15, band 15q14 — in an intron of SPRED1.
What each result means
A/ATwo copies of the version the research linked to Birth weight. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Birth weight. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Birth weight. This is the starting point the study compared everyone against.
The British journal of ophthalmology · 2020 · PMID 31097437
Questions about rs11853312
What is rs11853312?
rs11853312 is a single position in the genome, in or near the SPRED1 gene. Published research associates it with birth weight. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11853312 linked to?
On MyGeneLog this position is linked to Birth Weight. The research behind each link, and its sources, are set out on that condition page.
Does having rs11853312 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11853312 come from?
GWAS Catalog, The British journal of ophthalmology 2020, PMID:31097437. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 5212Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others2Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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