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Hemoglobin levels

HNF1A · rs1182933

Where this position leads

Condition: Blood Cell Counts

rs1182933 Condition: Blood Cell Counts Blood Cell Counts Condition rs1182933 rs1182933 HNF1A

What the study found

Who was studied 684,122 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.024 higher; p = 2 × 10−23.

Where it sits Chromosome 12, band 12q24.31 — between genes, 0.3 kb from C12orf43.

What each result means

C/C No copy of the version the research linked to Hemoglobin levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Hemoglobin levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Hemoglobin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1182933

What is rs1182933?

rs1182933 is a single position in the genome, in or near the HNF1A gene. Published research associates it with hemoglobin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1182933 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs1182933 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1182933 come from?

GWAS Catalog, Communications biology 2020, PMID:32327693. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hemoglobin levels (rs1182933). MyGeneLog™. https://www.mygenelog.com/variants/rs1182933

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