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Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)

DAGLA · rs11827215

What the study found

Who was studied 717 Singaporean Chinese ancestry myocardial infarction cases, 644 Singaporean Chinese ancestry controls.

The effect Each copy of the G allele shifted the measure 0.0394 higher (95% confidence interval 0.027-0.052); p = 2 × 10−10.

How common The G allele had a frequency of about 79% in the people studied.

Where it sits Chromosome 11, band 11q12.2 — in an intron of DAGLA.

What each result means

A/A No copy of the version the research linked to Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11827215

What is rs11827215?

rs11827215 is a single position in the genome, in or near the DAGLA gene. Published research associates it with plasma omega-6 polyunsaturated fatty acid levels (linoleic acid). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11827215 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11827215 come from?

GWAS Catalog, Genes & nutrition 2015, PMID:26584805. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) (rs11827215). MyGeneLog™. https://www.mygenelog.com/variants/rs11827215

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