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Triglycerides-Blood Pressure (TG-BP)

ZNF259 · rs11823543

Where this position leads

Condition: Blood Pressure

rs11823543 Condition: Blood Pressure Blood Pressure Condition rs11823543 rs11823543 ZNF259

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Triglycerides-Blood Pressure (TG-BP) compared to the general population. (GWAS Catalog, Diabetes 2011, PMID:21386085)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Triglycerides-Blood Pressure (TG-BP). (GWAS Catalog, Diabetes 2011, PMID:21386085)
G/G Published research associates this genotype with typical/baseline likelihood of Triglycerides-Blood Pressure (TG-BP) — no copies of the reported risk allele. (GWAS Catalog, Diabetes 2011, PMID:21386085)
Source
A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium
Kraja AT, Vaidya D, Pankow JS, Goodarzi MO, Assimes TL, Kullo IJ, Sovio U, Mathias RA, Sun YV, Franceschini N, Absher D, Li G
and 27 more — show all
Zhang Q, Feitosa MF, Glazer NL, Haritunians T, Hartikainen AL, Knowles JW, North KE, Iribarren C, Kral B, Yanek L, O'Reilly PF, McCarthy MI, Jaquish C, Couper DJ, Chakravarti A, Psaty BM, Becker LC, Province MA, Boerwinkle E, Quertermous T, Palotie L, Jarvelin MR, Becker DM, Kardia SL, Rotter JI, Chen YD, Borecki IB
Diabetes · 2011 · PMID 21386085 · open access

Questions about rs11823543

What is rs11823543?

rs11823543 is a single position in the genome, in or near the ZNF259 gene. Published research associates it with triglycerides-blood pressure (tg-bp). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11823543 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs11823543 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11823543 come from?

GWAS Catalog, Diabetes 2011, PMID:21386085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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