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Whole body fat free mass (UKB data field 23101)

ARHGEF12 · rs11823264

What the study found

Who was studied 337,739 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0112 lower (95% confidence interval 0.0077-0.0146); p = 3 × 10−10.

Where it sits Chromosome 11, band 11q23.3 — in an intron of ARHGEF12.

What each result means

A/A Two copies of the version the research linked to Whole body fat free mass (UKB data field 23101). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Whole body fat free mass (UKB data field 23101). That is a smaller link than two copies.
G/G No copy of the version the research linked to Whole body fat free mass (UKB data field 23101). This is the starting point the study compared everyone against.
Source

Questions about rs11823264

What is rs11823264?

rs11823264 is a single position in the genome, in or near the ARHGEF12 gene. Published research associates it with whole body fat free mass (ukb data field 23101). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11823264 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11823264 come from?

GWAS Catalog, Scientific reports 2024, PMID:38538606. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Whole body fat free mass (UKB data field 23101) (rs11823264). MyGeneLog™. https://www.mygenelog.com/variants/rs11823264

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