Sensitive

Transcobalamin-1 level in Chronic kidney disease with hypertension and no diabetes (11232_46)

TCN1 · rs11822978

What the study found

Who was studied 466 African American individuals.

The effect Each copy of the T allele shifted the measure 1.65 lower (95% confidence interval 1.4-1.9); p = 2 × 10−36.

How common The T allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 11, band 11q12.1 — in an intron of TCN1.

What each result means

C/C No copy of the version the research linked to Transcobalamin-1 level in Chronic kidney disease with hypertension and no diabetes (11232_46). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Transcobalamin-1 level in Chronic kidney disease with hypertension and no diabetes (11232_46). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Transcobalamin-1 level in Chronic kidney disease with hypertension and no diabetes (11232_46). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11822978

What is rs11822978?

rs11822978 is a single position in the genome, in or near the TCN1 gene. Published research associates it with transcobalamin-1 level in chronic kidney disease with hypertension and no diabetes (11232_46). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11822978 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11822978 come from?

GWAS Catalog, Kidney international 2022, PMID:35870639. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Transcobalamin-1 level in Chronic kidney disease with hypertension and no diabetes (11232_46) (rs11822978). MyGeneLog™. https://www.mygenelog.com/variants/rs11822978

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