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Immature reticulocyte fraction (UKB data field 30280)

LINC00324 · rs118182078

Where this position leads

Condition: Celiac Disease

rs118182078 Condition: Celiac Disease Celiac Disease Condition rs118182078 rs118182078 LINC00324

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.04 lower (95% confidence interval 0.028-0.052); p = 3 × 10−12.

How common The A allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 17, band 17p13.1 — in a non-coding transcript of LINC00324.

What each result means

A/A Two copies of the version the research linked to Immature reticulocyte fraction (UKB data field 30280). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Immature reticulocyte fraction (UKB data field 30280). That is a smaller link than two copies.
G/G No copy of the version the research linked to Immature reticulocyte fraction (UKB data field 30280). This is the starting point the study compared everyone against.
Source

Questions about rs118182078

What is rs118182078?

rs118182078 is a single position in the genome, in or near the LINC00324 gene. Published research associates it with immature reticulocyte fraction (ukb data field 30280). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs118182078 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs118182078 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs118182078 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Immature reticulocyte fraction (UKB data field 30280) (rs118182078). MyGeneLog™. https://www.mygenelog.com/variants/rs118182078

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