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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 14,296 European ancestry individuals; replicated in 5,698 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.249 lower (95% confidence interval 0.18-0.32); p = 4 × 10−11.
How common The T allele had a frequency of about 2% in the people studied.
Where it sits Chromosome 16, band 16p11.2 — between genes, 3.8 kb from Y_RNA.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of X-13553 levels — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with X-13553 levels.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of X-13553 levels compared to the general population.
Nature medicine · 2022 · PMID 36357675 · open access
Questions about rs118154869
What is rs118154869?
rs118154869 is a single position in the genome, in or near the near Y_RNA gene. Published research associates it with x-13553 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs118154869 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs118154869 come from?
GWAS Catalog, Nature medicine 2022, PMID:36357675. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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