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CLPS protein levels

near PACSIN1 · rs118136297

Where this position leads

Condition: Celiac Disease

rs118136297 Condition: Celiac Disease Celiac Disease Condition rs118136297 rs118136297 near PACSIN1

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0761 higher (95% confidence interval 0.053-0.099); p = 2 × 10−12.

How common The T allele had a frequency of about 7% in the people studied.

Where it sits Chromosome 6, band 6p21.31 — between genes, 8 kb from PACSIN1.

What each result means

C/C No copy of the version the research linked to CLPS protein levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to CLPS protein levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to CLPS protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs118136297

What is rs118136297?

rs118136297 is a single position in the genome, in or near the near PACSIN1 gene. Published research associates it with clps protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs118136297 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs118136297 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs118136297 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

CLPS protein levels (rs118136297). MyGeneLog™. https://www.mygenelog.com/variants/rs118136297

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