Standard
Logical memory (immediate recall) in mild cognitive impairment
WRN · rs118130881
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Logical memory (immediate recall) in mild cognitive impairment — no copies of the reported risk allele.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Logical memory (immediate recall) in mild cognitive impairment.
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Logical memory (immediate recall) in mild cognitive impairment compared to the general population.
Source
Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages
Chung J,
Wang X,
Maruyama T,
Ma Y,
Zhang X,
Mez J,
Sherva R,
Takeyama H,
Lunetta KL,
Farrer LA,
Jun GR
Alzheimer's & dementia : the journal of the Alzheimer's Association · 2018 · PMID 29274321
Questions about rs118130881
What is rs118130881?
rs118130881 is a single position in the genome, in or near the WRN gene. Published research associates it with logical memory (immediate recall) in mild cognitive impairment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs118130881 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs118130881 come from?
GWAS Catalog, Alzheimers Dement 2017, PMID:29274321. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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