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White blood cell count

near KIRREL1 · rs11809289

What the study found

Who was studied 6,007 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals.

The effect Each copy of the G allele shifted the measure 0.17 lower (95% confidence interval 0.11-0.23); p = 7 × 10−10.

How common The G allele had a frequency of about 13% in the people studied.

Where it sits Chromosome 1, band 1q23.1 — between genes, 12.3 kb from KIRREL1.

What each result means

A/A No copy of the version the research linked to White blood cell count. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to White blood cell count. That is a smaller link than two copies.
G/G Two copies of the version the research linked to White blood cell count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11809289

What is rs11809289?

rs11809289 is a single position in the genome, in or near the near KIRREL1 gene. Published research associates it with white blood cell count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11809289 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11809289 come from?

GWAS Catalog, Nature communications 2021, PMID:33623009. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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White blood cell count (rs11809289). MyGeneLog™. https://www.mygenelog.com/variants/rs11809289

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