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Cerebellar grey matter morphology (MOSTest)

ZNF462 · rs118017926

What the study found

Who was studied 27,302 European ancestry individuals; replicated in 11,264 European ancestry individuals.

The effect The reported allele is C; the catalogue records no effect size ; p = 6 × 10−9.

Where it sits Chromosome 9, band 9q31.2 — in an intron of ZNF462.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cerebellar grey matter morphology (MOSTest) compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cerebellar grey matter morphology (MOSTest).
T/T Published research associates this genotype with typical/baseline likelihood of Cerebellar grey matter morphology (MOSTest) — no copies of the reported risk allele.
Source

Questions about rs118017926

What is rs118017926?

rs118017926 is a single position in the genome, in or near the ZNF462 gene. Published research associates it with cerebellar grey matter morphology (mostest). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs118017926 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs118017926 come from?

GWAS Catalog, Communications biology 2026, PMID:41703085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cerebellar grey matter morphology (MOSTest) (rs118017926). MyGeneLog™. https://www.mygenelog.com/variants/rs118017926

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