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Protein C levels

BAZIB · rs1178979

What the study found

Who was studied 10,778 European ancestry individuals, 2,706 African American individuals.

The effect Each copy of the C allele shifted the measure 0.06 μg/mL lower; p = 3 × 10−8.

How common The C allele had a frequency of about 19% in the people studied.

Where it sits Chromosome 7, band 7q11.23 — in the 3′ untranslated region of BAZ1B.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Protein C levels compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Protein C levels.
T/T Published research associates this genotype with typical/baseline likelihood of Protein C levels — no copies of the reported risk allele.
Source

Questions about rs1178979

What is rs1178979?

rs1178979 is a single position in the genome, in or near the BAZIB gene. Published research associates it with protein c levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1178979 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1178979 come from?

GWAS Catalog, Arterioscler Thromb Vasc Biol 2017, PMID:28082259. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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