Standard

Physical function (baseline)

LRCH4 · rs117763269

What the study found

Who was studied 405,979 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0249 higher (95% confidence interval 0.017-0.033); p = 3 × 10−10.

How common The G allele had a frequency of about 98% in the people studied.

Where it sits Chromosome 7, band 7q22.1 — in an intron of LRCH4.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Physical function (baseline) — no copies of the reported risk allele.
C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Physical function (baseline).
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Physical function (baseline) compared to the general population.
Source

Questions about rs117763269

What is rs117763269?

rs117763269 is a single position in the genome, in or near the LRCH4 gene. Published research associates it with physical function (baseline). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs117763269 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs117763269 come from?

GWAS Catalog, Nature communications 2025, PMID:40374629. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Physical function (baseline) (rs117763269). MyGeneLog™. https://www.mygenelog.com/variants/rs117763269

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