Sensitive

Response to paliperidone in schizophrenia (negative Marder score)

MIR100HG · rs117752187

Where this position leads

Condition: Schizophrenia

rs117752187 Condition: Schizophrenia Schizophrenia Condition rs117752187 rs117752187 MIR100HG

What the study found

Who was studied 1,390 European ancestry cases.

The effect Each copy of the G allele shifted the measure 8 lower; p = 6 × 10−11.

Where it sits Chromosome 11, band 11q24.1 — in an intron of MIR100HG.

What each result means

A/A No copy of the version the research linked to Response to paliperidone in schizophrenia (negative Marder score). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Response to paliperidone in schizophrenia (negative Marder score). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Response to paliperidone in schizophrenia (negative Marder score). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs117752187

What is rs117752187?

rs117752187 is a single position in the genome, in or near the MIR100HG gene. Published research associates it with response to paliperidone in schizophrenia (negative marder score). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs117752187 linked to?

On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.

Does having rs117752187 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs117752187 come from?

GWAS Catalog, Pharmacogenetics and genomics 2017, PMID:27846195. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Response to paliperidone in schizophrenia (negative Marder score) (rs117752187). MyGeneLog™. https://www.mygenelog.com/variants/rs117752187

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