Standard

Left ventricular end systole anterolateral wall thickness

ATP2B1 · rs117742247

What the study found

Who was studied 41,646 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.05 lower (95% confidence interval 0.03-0.07); p = 1 × 10−8.

Where it sits Chromosome 12, band 12q21.33 — in an intron of ATP2B1.

What each result means

C/C No copy of the version the research linked to Left ventricular end systole anterolateral wall thickness. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Left ventricular end systole anterolateral wall thickness. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Left ventricular end systole anterolateral wall thickness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs117742247

What is rs117742247?

rs117742247 is a single position in the genome, in or near the ATP2B1 gene. Published research associates it with left ventricular end systole anterolateral wall thickness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs117742247 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs117742247 come from?

GWAS Catalog, Nature communications 2023, PMID:38036550. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Left ventricular end systole anterolateral wall thickness (rs117742247). MyGeneLog™. https://www.mygenelog.com/variants/rs117742247

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