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Who was studied 341,805 European ancestry individuals, 6,006 African ancestry individuals, 7,316 South Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0324 lower (95% confidence interval 0.023-0.042); p = 4 × 10−11.
Where it sits Chromosome 7, band 7p15.3 — in an intron of KLHL7.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of C-reactive protein levels compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with C-reactive protein levels.
G/GPublished research associates this genotype with typical/baseline likelihood of C-reactive protein levels — no copies of the reported risk allele.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs11770879
What is rs11770879?
rs11770879 is a single position in the genome, in or near the KLHL7 gene. Published research associates it with c-reactive protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11770879 linked to?
On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs11770879 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11770879 come from?
GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
C-reactive protein levels (rs11770879). MyGeneLog™. https://www.mygenelog.com/variants/rs11770879