Who was studied 25,042 European and unknown ancestry cases, 34,915 European and unknown ancestry controls.
The effect
Each copy of the A allele carried 1.09 times the odds of Inflammatory bowel disease (95% confidence interval 1.06-1.12); p = 4 × 10−8.
How common The A allele had a frequency of about 82% in the people studied.
Where it sits Chromosome 7, band 7p22.1 — in an intron of GRID2IP.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Inflammatory bowel disease compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Inflammatory bowel disease.
G/GPublished research associates this genotype with typical/baseline likelihood of Inflammatory bowel disease — no copies of the reported risk allele.
Nature genetics · 2017 · PMID 28067908 · open access
Questions about rs11768365
What is rs11768365?
rs11768365 is a single position in the genome, in or near the FLJ20306 gene. Published research associates it with inflammatory bowel disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11768365 linked to?
On MyGeneLog this position is linked to Inflammatory Bowel Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs11768365 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11768365 come from?
GWAS Catalog, Nat Genet 2017, PMID:28067908. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.