Standard

Hand grip strength

MAD1L1 · rs11766468

Where this position leads

Condition: Hand Grip Strength

rs11766468 Condition: Hand Grip Strength Hand Grip Strength Condition rs11766468 rs11766468 MAD1L1

What the study found

Who was studied 334,825 British ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.003 higher (95% confidence interval 0.0022-0.0038); p = 8 × 10−12.

How common The A allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 7, band 7p22.3 — in an intron of MAD1L1.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hand grip strength compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hand grip strength.
G/G Published research associates this genotype with typical/baseline likelihood of Hand grip strength — no copies of the reported risk allele.
Source

Questions about rs11766468

What is rs11766468?

rs11766468 is a single position in the genome, in or near the MAD1L1 gene. Published research associates it with hand grip strength. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11766468 linked to?

On MyGeneLog this position is linked to Hand Grip Strength. The research behind each link, and its sources, are set out on that condition page.

Does having rs11766468 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11766468 come from?

GWAS Catalog, Sci Rep 2018, PMID:29691431. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hand grip strength (rs11766468). MyGeneLog™. https://www.mygenelog.com/variants/rs11766468

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