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Who was studied 817 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 4.41 higher (95% confidence interval 2.96-5.86); p = 4 × 10−9.
Where it sits Chromosome 7, band 7q32.1 — in an intron of AHCYL2.
What each result means
C/CNo copy of the version the research linked to Response to fenofibrate. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Response to fenofibrate. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Response to fenofibrate. That is the strongest link of the three results. A link in a study is not a diagnosis.
Pharmacogenetics and genomics · 2012 · PMID 22890011
Questions about rs11766298
What is rs11766298?
rs11766298 is a single position in the genome, in or near the AHCYL2 gene. Published research associates it with response to fenofibrate. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11766298 linked to?
On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does rs11766298 affect how medicines work?
AHCYL2 carries pharmacogenomic findings for Fenofibrate. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs11766298 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11766298 come from?
GWAS Catalog, Pharmacogenet Genomics 2012, PMID:22890011. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 4532129223219Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity2Meta AI9Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others19Total45Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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Response to fenofibrate (rs11766298). MyGeneLog™. https://www.mygenelog.com/variants/rs11766298