Standard

TYMP protein levels

SYCE3 · rs117637509

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.18 lower (95% confidence interval 0.15-0.21); p = 5 × 10−39.

How common The A allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 22, band 22q13.33 — in an intron of SYCE3.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of TYMP protein levels compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with TYMP protein levels.
G/G Published research associates this genotype with typical/baseline likelihood of TYMP protein levels — no copies of the reported risk allele.
Source

Questions about rs117637509

What is rs117637509?

rs117637509 is a single position in the genome, in or near the SYCE3 gene. Published research associates it with tymp protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs117637509 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs117637509 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

TYMP protein levels (rs117637509). MyGeneLog™. https://www.mygenelog.com/variants/rs117637509

← See all variants