Sensitive
Vogt-Koyanagi-Harada syndrome
C1orf141 · rs117633859
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Vogt-Koyanagi-Harada syndrome — no copies of the reported risk allele.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Vogt-Koyanagi-Harada syndrome.
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Vogt-Koyanagi-Harada syndrome compared to the general population.
Source
Genome-wide association analysis of Vogt-Koyanagi-Harada syndrome identifies two new susceptibility loci at 1p31.2 and 10q21.3
Hou S,
Du L,
Lei B,
Pang CP,
Zhang M,
Zhuang W,
Zhang M,
Huang L,
Gong B,
Wang M,
Zhang Q,
Hu K
and 17 more — show all
Zhou Q,
Qi J,
Wang C,
Tian Y,
Ye Z,
Liang L,
Yu H,
Li H,
Zhou Y,
Cao Q,
Liu Y,
Bai L,
Liao D,
Kijlstra A,
Xu J,
Yang Z,
Yang P
Nature genetics · 2014 · PMID 25108386
Questions about rs117633859
What is rs117633859?
rs117633859 is a single position in the genome, in or near the C1orf141 gene. Published research associates it with vogt-koyanagi-harada syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs117633859 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs117633859 come from?
GWAS Catalog, Nat Genet 2014, PMID:25108386. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants