1 412226124220Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple4China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others20Total41Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 774 Han Chinese ancestry cases, 2,009 Han Chinese ancestry controls; replicated in 764 Han Chinese ancestry cases, 3594 Han Chinese ancestry controls.
The effect
Each copy of the G allele carried 1.82 times the odds of Vogt-Koyanagi-Harada syndrome (95% confidence interval 1.60–2.05); p = 3 × 10−21.
How common The G allele had a frequency of about 10% in the people studied.
Where it sits Chromosome 1, band 1p31.3 — in an intron of IL23R.
What each result means
A/ANo copy of the version the research linked to Vogt-Koyanagi-Harada syndrome. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Vogt-Koyanagi-Harada syndrome. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Vogt-Koyanagi-Harada syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs117633859 is a single position in the genome, in or near the C1orf141 gene. Published research associates it with vogt-koyanagi-harada syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs117633859 linked to?
On MyGeneLog this position is linked to Vogt-Koyanagi-Harada Syndrome. The research behind each link, and its sources, are set out on that condition page.
Does having rs117633859 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs117633859 come from?
GWAS Catalog, Nat Genet 2014, PMID:25108386. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 412226124220Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple4China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others20Total41Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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