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Who was studied 24,087 European ancestry cases, 55,058 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 6.67 z-score lower; p = 3 × 10−11.
Where it sits Chromosome 7, band 7q35 — in an intron of EPHA1-AS1.
What each result means
C/CNo copy of the version the research linked to Alzheimer's disease (late onset). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Alzheimer's disease (late onset). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Alzheimer's disease (late onset). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs11763230 is a single position in the genome, in or near the EPHA1 gene. Published research associates it with alzheimer's disease (late onset). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11763230 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs11763230 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11763230 come from?
GWAS Catalog, Nature genetics 2019, PMID:30617256. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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