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Cholesteryl Esters to Total Lipids in Large VLDL percentage

near KLF14 · rs11762784

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs11762784 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs11762784 rs11762784 near KLF14

What the study found

Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.

The effect Each copy of the A allele shifted the measure 0.02 % higher (95% confidence interval 0.02-0.02); p = 3 × 10−33.

Where it sits Chromosome 7, band 7q32.2 — between genes, 5.7 kb from KLF14.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cholesteryl Esters to Total Lipids in Large VLDL percentage compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cholesteryl Esters to Total Lipids in Large VLDL percentage.
G/G Published research associates this genotype with typical/baseline likelihood of Cholesteryl Esters to Total Lipids in Large VLDL percentage — no copies of the reported risk allele.
Source

Questions about rs11762784

What is rs11762784?

rs11762784 is a single position in the genome, in or near the near KLF14 gene. Published research associates it with cholesteryl esters to total lipids in large vldl percentage. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11762784 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs11762784 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11762784 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cholesteryl Esters to Total Lipids in Large VLDL percentage (rs11762784). MyGeneLog™. https://www.mygenelog.com/variants/rs11762784

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