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Thyroid peroxidase antibody levels in pregnancy

IFT81 · rs117624317

What the study found

Who was studied 60,225 Chinese ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.223 higher (95% confidence interval 0.15-0.29); p = 6 × 10−10.

How common The T allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 12, band 12q24.11 — in an intron of IFT81.

What each result means

C/C No copy of the version the research linked to Thyroid peroxidase antibody levels in pregnancy. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Thyroid peroxidase antibody levels in pregnancy. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Thyroid peroxidase antibody levels in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs117624317

What is rs117624317?

rs117624317 is a single position in the genome, in or near the IFT81 gene. Published research associates it with thyroid peroxidase antibody levels in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs117624317 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs117624317 come from?

GWAS Catalog, Nature communications 2024, PMID:39266554. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Thyroid peroxidase antibody levels in pregnancy (rs117624317). MyGeneLog™. https://www.mygenelog.com/variants/rs117624317

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