Sensitive

Systemic lupus erythematosus (MTAG)

near SPMIP7 · rs11761913

Where this position leads

Condition: Systemic Lupus Erythematosus

rs11761913 Condition: Systemic Lupus Erythematosus Systemic Lupus Erythematosus Condition rs11761913 rs11761913 near SPMIP7

What the study found

Who was studied at least 5,877 East Asian ancestry cases, at least 188,588 East Asian ancestry controls, at least 14,355 European ancestry cases, at least 505,956 European ancestry controls, at least 1,393 admixed American ancestry cases, at least 2,327 admixed American ancestry controls (MTAG boosted by autoimmune diseases samples).

The effect Each copy of the C allele shifted the measure 0.057 higher (95% confidence interval 0.038-0.076); p = 4 × 10−9.

Where it sits Chromosome 7, band 7p12.2 — between genes, 50.2 kb from SPMIP7.

What each result means

C/C Two copies of the version the research linked to Systemic lupus erythematosus (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Systemic lupus erythematosus (MTAG). That is a smaller link than two copies.
T/T No copy of the version the research linked to Systemic lupus erythematosus (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs11761913

What is rs11761913?

rs11761913 is a single position in the genome, in or near the near SPMIP7 gene. Published research associates it with systemic lupus erythematosus (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11761913 linked to?

On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.

Does having rs11761913 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11761913 come from?

GWAS Catalog, Nature communications 2023, PMID:36750564. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systemic lupus erythematosus (MTAG) (rs11761913). MyGeneLog™. https://www.mygenelog.com/variants/rs11761913

← See all variants