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Monounsaturated fatty acid levels

MLXIPL · rs11760752

Strength of the evidence

1 / 4

Its strongest genetic-study result is p = 10−8, with 3 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 239,268 European ancestry individuals.

The effect The reported allele is A; the catalogue records no effect size ; p = 2 × 10−8.

Where it sits Chromosome 7, band 7q11.23 — in an intron of MLXIPL.

What each result means

A/A Two copies of the version the research linked to Monounsaturated fatty acid levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Monounsaturated fatty acid levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to Monounsaturated fatty acid levels. This is the starting point the study compared everyone against.
Source

Questions about rs11760752

What is rs11760752?

rs11760752 is a single position in the genome, in or near the MLXIPL gene. Published research associates it with monounsaturated fatty acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11760752 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11760752 come from?

GWAS Catalog, HGG advances 2025, PMID:40545721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Monounsaturated fatty acid levels (rs11760752). MyGeneLog™. https://www.mygenelog.com/variants/rs11760752

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