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CD163 protein levels

CCDC162P · rs11759230

Where this position leads

Condition: Celiac Disease

rs11759230 Condition: Celiac Disease Celiac Disease Condition rs11759230 rs11759230 CCDC162P

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0475 lower (95% confidence interval 0.036-0.059); p = 1 × 10−22.

How common The C allele had a frequency of about 34% in the people studied.

Where it sits Chromosome 6, band 6q21 — in an intron of CCDC162P.

What each result means

A/A No copy of the version the research linked to CD163 protein levels. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to CD163 protein levels. That is a smaller link than two copies.
C/C Two copies of the version the research linked to CD163 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11759230

What is rs11759230?

rs11759230 is a single position in the genome, in or near the CCDC162P gene. Published research associates it with cd163 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11759230 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs11759230 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11759230 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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CD163 protein levels (rs11759230). MyGeneLog™. https://www.mygenelog.com/variants/rs11759230

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