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Sex hormone-binding globulin levels

near PAG1 · rs117562850

What the study found

Who was studied 310,323 European ancestry individuals, 5,523 African ancestry individuals, 6,638 South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0434 higher (95% confidence interval 0.031-0.056); p = 1 × 10−11.

Where it sits Chromosome 8, band 8q21.13 — between genes, 43.7 kb from PAG1.

What each result means

A/A Two copies of the version the research linked to Sex hormone-binding globulin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Sex hormone-binding globulin levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Sex hormone-binding globulin levels. This is the starting point the study compared everyone against.
Source

Questions about rs117562850

What is rs117562850?

rs117562850 is a single position in the genome, in or near the near PAG1 gene. Published research associates it with sex hormone-binding globulin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs117562850 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs117562850 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Sex hormone-binding globulin levels (rs117562850). MyGeneLog™. https://www.mygenelog.com/variants/rs117562850

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