Sensitive

Inflammatory bowel disease

near C6orf15 · rs11754821

Where this position leads

Condition: Inflammatory Bowel Disease

rs11754821 Condition: Inflammatory Bowel Disease Inflammatory Bowel Disease Condition rs11754821 rs11754821 near C6orf15

What the study found

Who was studied 18,158 European ancestry female cases, 22,345 European ancestry female controls.

The effect Each copy of the C allele carried 1.16 times the odds of Inflammatory bowel disease (95% confidence interval 1.103-1.212); p = 2 × 10−9.

Where it sits Chromosome 6, band 6p21.33 — between genes, 1.4 kb from C6orf15.

What each result means

C/C Two copies of the version the research linked to Inflammatory bowel disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Inflammatory bowel disease. That is a smaller link than two copies.
G/G No copy of the version the research linked to Inflammatory bowel disease. This is the starting point the study compared everyone against.
Source

Questions about rs11754821

What is rs11754821?

rs11754821 is a single position in the genome, in or near the near C6orf15 gene. Published research associates it with inflammatory bowel disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11754821 linked to?

On MyGeneLog this position is linked to Inflammatory Bowel Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs11754821 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11754821 come from?

GWAS Catalog, Inflammatory bowel diseases 2023, PMID:37262302. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Inflammatory bowel disease (rs11754821). MyGeneLog™. https://www.mygenelog.com/variants/rs11754821

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