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Estimated glomerular filtration rate

SLC22A2 · rs11753349

What the study found

Who was studied 105,607 African American, West African or admixed African individuals, 40,125 Hispanic/Latino or American Indian ancestry individuals.

The effect Each copy of the G allele shifted the measure 9.06 z score lower; p = 1 × 10−19.

Where it sits Chromosome 6, band 6q25.3 — in an intron of SLC22A2.

What each result means

A/A No copy of the version the research linked to Estimated glomerular filtration rate. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Estimated glomerular filtration rate. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Estimated glomerular filtration rate. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11753349

What is rs11753349?

rs11753349 is a single position in the genome, in or near the SLC22A2 gene. Published research associates it with estimated glomerular filtration rate. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11753349 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11753349 come from?

GWAS Catalog, Cell genomics 2024, PMID:38190104. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Estimated glomerular filtration rate (rs11753349). MyGeneLog™. https://www.mygenelog.com/variants/rs11753349

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