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Biological sex

RGS2-AS1 · rs1175109

What the study found

Who was studied 1,301,549 European ancestry cases, 1,160,583 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.0114 lower (95% confidence interval 0.0079-0.015); p = 4 × 10−10.

Where it sits Chromosome 1, band 1q31.2 — inside RGS2-AS1.

What each result means

A/A No copy of the version the research linked to Biological sex. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Biological sex. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Biological sex. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1175109

What is rs1175109?

rs1175109 is a single position in the genome, in or near the RGS2-AS1 gene. Published research associates it with biological sex. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1175109 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1175109 come from?

GWAS Catalog, Nature genetics 2021, PMID:33888908. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Biological sex (rs1175109). MyGeneLog™. https://www.mygenelog.com/variants/rs1175109

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