0 27223119Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others19Total27Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 315,133 European ancestry individuals, 74,970 East Asian ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0337 lower (95% confidence interval 0.022-0.045); p = 4 × 10−9.
Where it sits Chromosome 17, band 17q21.31 — in an intron of MAPT.
What each result means
C/CTwo copies of the version the research linked to HDL cholesterol. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to HDL cholesterol. That is a smaller link than two copies.
T/TNo copy of the version the research linked to HDL cholesterol. This is the starting point the study compared everyone against.
rs117499775 is a single position in the genome, in or near the MAPT gene. Published research associates it with hdl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs117499775 linked to?
On MyGeneLog this position is linked to Colon Polyp, Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does having rs117499775 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs117499775 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 27223119Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others19Total27Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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