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Who was studied 1,551 Han Chinese ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.54 lower (95% confidence interval 0.38-0.7); p = 6 × 10−11.
How common The A allele had a frequency of about 5% in the people studied.
Where it sits Chromosome 4, band 4q22.3 — in an intron of LINC02267.
What each result means
A/ATwo copies of the version the research linked to Hypoxanthine levels in coronary artery disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Hypoxanthine levels in coronary artery disease. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Hypoxanthine levels in coronary artery disease. This is the starting point the study compared everyone against.
Clinical and translational medicine · 2021 · PMID 33634981 · open access
Questions about rs117445861
What is rs117445861?
rs117445861 is a single position in the genome, in or near the LINC02267 gene. Published research associates it with hypoxanthine levels in coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs117445861 linked to?
On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs117445861 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs117445861 come from?
GWAS Catalog, Clinical and translational medicine 2021, PMID:33634981. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Hypoxanthine levels in coronary artery disease (rs117445861). MyGeneLog™. https://www.mygenelog.com/variants/rs117445861