TAC3 · rs117444538
Where this position leads
Condition: Blood Cell Counts
What the study found
Who was studied 116,666 British ancestry individuals.
The effect Each copy of the C allele shifted the measure 0.0616 higher (95% confidence interval 0.04-0.083); p = 5 × 10−8.
Where it sits Chromosome 12, band 12q13.3 — in an intron of TAC3.
rs117444538 is a single position in the genome, in or near the TAC3 gene. Published research associates it with red cell distribution width. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, PLoS One 2017, PMID:28957414. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Red cell distribution width (rs117444538). MyGeneLog™. https://www.mygenelog.com/variants/rs117444538