0 1522110Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 8,021 European ancestry cases, 16,489 European ancestry controls, 2,495 East Asian ancestry cases, 4,283 East Asian ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.236 lower (95% confidence interval 0.19-0.28); p = 4 × 10−24.
Where it sits Chromosome 5, band 5p13.2 — between genes, 1.7 kb from IL7R.
What each result means
A/ATwo copies of the version the research linked to Primary biliary cholangitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Primary biliary cholangitis. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Primary biliary cholangitis. This is the starting point the study compared everyone against.
Journal of hepatology · 2021 · PMID 34033851 · open access
Questions about rs11742270
What is rs11742270?
rs11742270 is a single position in the genome, in or near the near IL7R gene. Published research associates it with primary biliary cholangitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11742270 linked to?
On MyGeneLog this position is linked to Primary Biliary Cholangitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs11742270 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11742270 come from?
GWAS Catalog, Journal of hepatology 2021, PMID:34033851. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1522110Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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