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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 217 European ancestry cases, 3,798 European ancestry controls; replicated in 313 European ancestry cases, 564 European ancestry controls.
The effect
Each copy of the C allele carried 4.90 times the odds of Waldenström macroglobulinemia / lymphoplasmacytic lymphoma (95% confidence interval 3.45-6.96); p = 9 × 10−19.
How common The C allele had a frequency of about 3% in the people studied.
Where it sits Chromosome 14, band 14q32.13 — between genes, 3.3 kb from LINC02318.
What each result means
C/CTwo copies of the version the research linked to Waldenström macroglobulinemia / lymphoplasmacytic lymphoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Waldenström macroglobulinemia / lymphoplasmacytic lymphoma. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Waldenström macroglobulinemia / lymphoplasmacytic lymphoma. This is the starting point the study compared everyone against.
Nature communications · 2018 · PMID 30305637 · open access
Questions about rs117410836
What is rs117410836?
rs117410836 is a single position in the genome, in or near the near LINC02318 gene. Published research associates it with waldenström macroglobulinemia / lymphoplasmacytic lymphoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs117410836 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs117410836 come from?
GWAS Catalog, Nature communications 2018, PMID:30305637. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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