Sensitive

Venous thromboembolism

near CD93 · rs117390891

Where this position leads

What the study found

Who was studied 71,771 European ancestry cases, 7,482 African ancestry cases, 189 South Asian ancestry cases, 507 East Asian ancestry cases, 1,720 Hispanic cases, 1,426,717 controls.

The effect Each copy of the T allele shifted the measure 0.0777 lower (95% confidence interval 0.062-0.094); p = 7 × 10⁻²².

How common The T allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 20, band 20p11.21 — in an intron of LINC03125.

What each result means

G/G No copy of the version the research linked to Venous thromboembolism. This is the starting point the study compared everyone against.

G/T One copy of the version the research linked to Venous thromboembolism. That is a smaller link than two copies.

T/T Two copies of the version the research linked to Venous thromboembolism. That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors

Thibord F, Klarin D, Brody JA, Chen MH, Levin MG, Chasman DI, Goode EL, Hveem K, Teder-Laving M, Martinez-Perez A, Aïssi D, Daian-Bacq D

and 76 more — show all

Ito K, Natarajan P, Lutsey PL, Nadkarni GN, de Vries PS, Cuellar-Partida G, Wolford BN, Pattee JW, Kooperberg C, Braekkan SK, Li-Gao R, Saut N, Sept C, Germain M, Judy RL, Wiggins KL, Ko D, O'Donnell CJ, Taylor KD, Giulianini F, De Andrade M, Nøst TH, Boland A, Empana JP, Koyama S, Gilliland T, Do R, Huffman JE, Wang X, Wang X, Zhou W, Manuel Soria J, Carlos Souto J, Pankratz N, Haessler J, Hindberg K, Rosendaal FR, Turman C, Olaso R, Kember RL, Bartz TM, Lynch JA, Heckbert SR, Armasu SM, Brumpton B, Smadja DM, Jouven X, Komuro I, Clapham KR, Loos RJF, Willer CJ, Sabater-Lleal M, Pankow JS, Reiner AP, Morelli VM, Ridker PM, Vlieg AVH, Deleuze JF, Kraft P, Rader DJ, Min Lee K, Psaty BM, Heidi Skogholt A, Emmerich J, Suchon P, Rich SS, Vy HMT, Tang W, Jackson RD, Hansen JB, Morange PE, Kabrhel C, Trégouët DA, Damrauer SM, Johnson AD, Smith NL

Global Biobank Meta-Analysis Initiative; Estonian Biobank Research Team; 23andMe Research Team; Biobank Japan; CHARGE Hemostasis Working Group

Circulation · 2022 · PMID 36154123

Questions about rs117390891

What is rs117390891?

rs117390891 is a single position in the genome, in or near the near CD93 gene. Published research associates it with venous thromboembolism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs117390891 linked to?

On MyGeneLog this position is linked to Venous Thromboembolism. The research behind each link, and its sources, are set out on that condition page.

Does having rs117390891 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs117390891 come from?

GWAS Catalog, Circulation 2022, PMID:36154123. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Venous thromboembolism (rs117390891). MyGeneLog™. https://www.mygenelog.com/variants/rs117390891

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