Sensitive

Venous thromboembolism recurrence in deep vein thrombosis as first VTE

near RNA5SP441 · rs117366080

Where this position leads

Condition: Venous Thromboembolism

rs117366080 Condition: Venous Thromboembolism Venous Thromboembolism Condition rs117366080 rs117366080 near RNA5SP4…

What the study found

Who was studied 1,074 European ancestry cases, 2,325 European ancestry controls.

The effect Each copy of the A allele carried 2.82 times the odds of Venous thromboembolism recurrence in deep vein thrombosis as first VTE (95% confidence interval 1.989194-3.9946); p = 6 × 10−9.

How common The A allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 17, band 17q21.2 — between genes, 5.1 kb from RNA5SP441.

What each result means

A/A Two copies of the version the research linked to Venous thromboembolism recurrence in deep vein thrombosis as first VTE. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Venous thromboembolism recurrence in deep vein thrombosis as first VTE. That is a smaller link than two copies.
G/G No copy of the version the research linked to Venous thromboembolism recurrence in deep vein thrombosis as first VTE. This is the starting point the study compared everyone against.
Source

Questions about rs117366080

What is rs117366080?

rs117366080 is a single position in the genome, in or near the near RNA5SP441 gene. Published research associates it with venous thromboembolism recurrence in deep vein thrombosis as first vte. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs117366080 linked to?

On MyGeneLog this position is linked to Venous Thromboembolism. The research behind each link, and its sources, are set out on that condition page.

Does having rs117366080 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs117366080 come from?

GWAS Catalog, Blood 2025, PMID:40811855. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Venous thromboembolism recurrence in deep vein thrombosis as first VTE (rs117366080). MyGeneLog™. https://www.mygenelog.com/variants/rs117366080

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