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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,703 Finnish ancestry ever smoker individuals from up to 739 families.
The effect
Each copy of the G allele shifted the measure 1.32 higher (95% confidence interval 0.85-1.79); p = 4 × 10−8.
How common The G allele had a frequency of about 2% in the people studied.
Where it sits Chromosome 18, band 18q12.3 — in an intron of SLC14A2.
What each result means
A/ANo copy of the version the research linked to Nicotine withdrawal symptom count. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Nicotine withdrawal symptom count. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Nicotine withdrawal symptom count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Addiction biology · 2019 · PMID 29532581 · open access
Questions about rs117354958
What is rs117354958?
rs117354958 is a single position in the genome, in or near the SLC14A2 gene. Published research associates it with nicotine withdrawal symptom count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs117354958 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs117354958 come from?
GWAS Catalog, Addict Biol 2018, PMID:29532581. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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