Sensitive

Osteoarthritis of the hip or knee

SLBP · rs11732213

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Osteoarthritis of the hip or knee — no copies of the reported risk allele.

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Osteoarthritis of the hip or knee.

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Osteoarthritis of the hip or knee compared to the general population.

Source

Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data

Tachmazidou I, Hatzikotoulas K, Southam L, Esparza-Gordillo J, Haberland V, Zheng J, Johnson T, Koprulu M, Zengini E, Steinberg J, Wilkinson JM, Bhatnagar S

and 9 more — show all

Hoffman JD, Buchan N, Süveges D, Yerges-Armstrong L, Smith GD, Gaunt TR, Scott RA, McCarthy LC, Zeggini E

arcOGEN Consortium

Nature genetics · 2019 · PMID 30664745 · open access

Questions about rs11732213

What is rs11732213?

rs11732213 is a single position in the genome, in or near the SLBP gene. Published research associates it with osteoarthritis of the hip or knee. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11732213 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11732213 come from?

GWAS Catalog, Nat Genet 2019, PMID:30664745. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

← See all variants