0 312Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total3Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 175,803 European ancestry cases, 644,862 European ancestry controls, 1,265 Japanese ancestry cases, 449 Southern Chinese ancestry cases, 3,330 Japanese ancestry controls, 981 Southern Chinese ancestry controls.
The effect
Each copy of the T allele carried 0.97 times the odds of Osteoarthritis (95% confidence interval 0.959169178-0.979304953); p = 5 × 10−9.
How common The T allele had a frequency of about 24% in the people studied.
Where it sits Chromosome 4, band 4q27 — between genes, 21.8 kb from PRDM5.
What each result means
G/GNo copy of the version the research linked to Osteoarthritis. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Osteoarthritis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Osteoarthritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs11729628 is a single position in the genome, in or near the near PRDM5 gene. Published research associates it with osteoarthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11729628 linked to?
On MyGeneLog this position is linked to Knee Osteoarthritis. The research behind each link, and its sources, are set out on that condition page.
Does having rs11729628 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11729628 come from?
GWAS Catalog, Cell 2021, PMID:34450027. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 312Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total3Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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