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Vaginal microbiome MetaCyc pathway (PWY-7456|mannan degradation)

COL22A1 · rs117290187

What the study found

Who was studied 315 Chinese ancestry individuals.

The effect Each copy of the T allele shifted the measure 1.57 higher (95% confidence interval 1.07-2.07); p = 3 × 10−9.

Where it sits Chromosome 8, band 8q24.23 — in an intron of COL22A1.

What each result means

C/C No copy of the version the research linked to Vaginal microbiome MetaCyc pathway (PWY-7456|mannan degradation). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Vaginal microbiome MetaCyc pathway (PWY-7456|mannan degradation). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Vaginal microbiome MetaCyc pathway (PWY-7456|mannan degradation). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs117290187

What is rs117290187?

rs117290187 is a single position in the genome, in or near the COL22A1 gene. Published research associates it with vaginal microbiome metacyc pathway (pwy-7456|mannan degradation). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs117290187 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs117290187 come from?

GWAS Catalog, mSystems 2021, PMID:34282934. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Vaginal microbiome MetaCyc pathway (PWY-7456|mannan degradation) (rs117290187). MyGeneLog™. https://www.mygenelog.com/variants/rs117290187

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