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ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 levels

CC2D2A · rs11728037

What the study found

Who was studied 2,935 Qatari ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.38 higher (95% confidence interval 0.32-0.44); p = 9 × 10−39.

How common The C allele had a frequency of about 31% in the people studied.

Where it sits Chromosome 4, band 4p15.32 — in an intron of CC2D2A.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 levels compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 levels.
T/T Published research associates this genotype with typical/baseline likelihood of ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 levels — no copies of the reported risk allele.
Source

Questions about rs11728037

What is rs11728037?

rs11728037 is a single position in the genome, in or near the CC2D2A gene. Published research associates it with adp-ribosyl cyclase/cyclic adp-ribose hydrolase 2 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11728037 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11728037 come from?

GWAS Catalog, Human molecular genetics 2023, PMID:36168886. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 levels (rs11728037). MyGeneLog™. https://www.mygenelog.com/variants/rs11728037

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