0 725Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others5Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 52,798 European ancestry individuals; replicated in 4,987 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.06 lower (95% confidence interval 0.052-0.068); p = 7 × 10−58.
How common The G allele had a frequency of about 83% in the people studied.
Where it sits Chromosome 4, band 4q26 — in an intron of KLHL2P1.
What each result means
A/ANo copy of the version the research linked to Retinal arteriolar tortuosity. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Retinal arteriolar tortuosity. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Retinal arteriolar tortuosity. That is the strongest link of the three results. A link in a study is not a diagnosis.
PLoS genetics · 2023 · PMID 36757925 · open access
Questions about rs11727963
What is rs11727963?
rs11727963 is a single position in the genome, in or near the KLHL2P1 gene. Published research associates it with retinal arteriolar tortuosity. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11727963 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11727963 come from?
GWAS Catalog, PLoS genetics 2023, PMID:36757925. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 725Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others5Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.