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Who was studied 44,383 European ancestry cases, 260,715 European ancestry controls; replicated in 4,854 European ancestry cases, 33,806 European ancestry controls, 998 Caribbean ancestry cases, 5,835 Caribbean ancestry controls, 3,368 East Asian ancestry cases, 191,045 East Asian ancestry controls.
The effect
Each copy of the G allele carried 3.05 times the odds of Asthma in lymphoma (95% confidence interval 2.67-3.44); p = 1 × 10−8.
How common The G allele had a frequency of about 3% in the people studied.
Where it sits Chromosome 21, band 21q22.3 — in an intron of PCNT.
What each result means
C/CNo copy of the version the research linked to Asthma in lymphoma. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Asthma in lymphoma. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Asthma in lymphoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2022 · PMID 36344522 · open access
Questions about rs117262476
What is rs117262476?
rs117262476 is a single position in the genome, in or near the PCNT gene. Published research associates it with asthma in lymphoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs117262476 linked to?
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
Does having rs117262476 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs117262476 come from?
GWAS Catalog, Nature communications 2022, PMID:36344522. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Asthma in lymphoma (rs117262476). MyGeneLog™. https://www.mygenelog.com/variants/rs117262476