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Medication use (calcium channel blockers)

FAT1 · rs11726072

Where this position leads

Condition: Medication Use as a Genetic Trait

rs11726072 Condition: Medication Use as a Genetic Trait Medication Use as a Genetic Trait Condition rs11726072 rs11726072 FAT1

What the study found

Who was studied 31,904 European ancestry cases, 172,474 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0679 lower (95% confidence interval 0.044-0.092); p = 3 × 10−8.

How common The A allele had a frequency of about 12% in the people studied.

Where it sits Chromosome 4, band 4q35.2 — in an intron of FAT1.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Medication use (calcium channel blockers) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Medication use (calcium channel blockers).
G/G Published research associates this genotype with typical/baseline likelihood of Medication use (calcium channel blockers) — no copies of the reported risk allele.
Source

Questions about rs11726072

What is rs11726072?

rs11726072 is a single position in the genome, in or near the FAT1 gene. Published research associates it with medication use (calcium channel blockers). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11726072 linked to?

On MyGeneLog this position is linked to Medication Use as a Genetic Trait. The research behind each link, and its sources, are set out on that condition page.

Does having rs11726072 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11726072 come from?

GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Medication use (calcium channel blockers) (rs11726072). MyGeneLog™. https://www.mygenelog.com/variants/rs11726072

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