0 5122Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 269,394 British ancestry brown hair individuals, 14,526 British ancestry black hair individuals.
The effect
The reported allele is T; the catalogue records no effect size
; p = 1 × 10−11.
How common The T allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 16, band 16q24.3 — in an intron of TCF25.
What each result means
C/CNo copy of the version the research linked to Brown vs. black hair color. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Brown vs. black hair color. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Brown vs. black hair color. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2018 · PMID 30531825 · open access
Questions about rs117243052
What is rs117243052?
rs117243052 is a single position in the genome, in or near the TCF25 gene. Published research associates it with brown vs. black hair color. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs117243052 linked to?
On MyGeneLog this position is linked to Hair Color. The research behind each link, and its sources, are set out on that condition page.
Does having rs117243052 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs117243052 come from?
GWAS Catalog, Nature communications 2018, PMID:30531825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 5122Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Brown vs. black hair color (rs117243052). MyGeneLog™. https://www.mygenelog.com/variants/rs117243052