Sensitive

Metabolic syndrome

near LPL · rs117227752

Where this position leads

Condition: Metabolic Syndrome

rs117227752 Condition: Metabolic Syndrome Metabolic Syndrome Condition rs117227752 rs117227752 near LPL

What the study found

Who was studied 24,171 Taiwanese ancestry cases, 83,059 Taiwanese ancestry controls.

The effect Each copy of the G allele shifted the measure 0.201 lower (95% confidence interval 0.16-0.24); p = 2 × 10−28.

How common The G allele had a frequency of about 9% in the people studied.

Where it sits Chromosome 8, band 8p21.3 — between genes, 19.1 kb from LPL.

What each result means

A/A No copy of the version the research linked to Metabolic syndrome. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Metabolic syndrome. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Metabolic syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs117227752

What is rs117227752?

rs117227752 is a single position in the genome, in or near the near LPL gene. Published research associates it with metabolic syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs117227752 linked to?

On MyGeneLog this position is linked to Metabolic Syndrome. The research behind each link, and its sources, are set out on that condition page.

Does having rs117227752 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs117227752 come from?

GWAS Catalog, Nutrients 2023, PMID:38201907. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Metabolic syndrome (rs117227752). MyGeneLog™. https://www.mygenelog.com/variants/rs117227752

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