0 232182226Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity1Meta AI8Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others6Total23Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 17,416 European ancestry cases, 375,455 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.161 higher (95% confidence interval 0.11-0.22); p = 1 × 10−8.
How common The T allele had a frequency of about 3% in the people studied.
Where it sits Chromosome 16, band 16q24.3 — in the 3′ untranslated region of DEF8.
What each result means
C/CNo copy of the version the research linked to Basal cell carcinoma. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Basal cell carcinoma. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Basal cell carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Genome medicine · 2021 · PMID 33549134 · open access
Questions about rs117204628
What is rs117204628?
rs117204628 is a single position in the genome, in or near the DEF8 gene. Published research associates it with basal cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs117204628 linked to?
On MyGeneLog this position is linked to Basal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs117204628 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs117204628 come from?
GWAS Catalog, Genome Med 2021, PMID:33549134. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 232182226Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity1Meta AI8Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others6Total23Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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